Nelson Textbook of Pediatrics 22nd Edition | Primary amenorrhea (no menarche by age 13 without secondary sexual characteristics, or by age 15 with normal development). Secondary amenorrhea (no menses for 3 cycles or 6 months). Etiologies: hypothalamic, pituitary, ovarian, uterine/outflow tract. Diagnostic algorithm: hCG, FSH, prolactin, TSH, pelvic ultrasound.
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