🩸 556.2 · Hemophagocytic Lymphohistiocytosis (HLH)

Nelson Textbook of Pediatrics 22nd Edition | Comprehensive coverage: Primary (familial) HLH (PRF1, UNC13D, STX11, STXBP2) and secondary HLH (infection, malignancy, rheumatologic), HLH-2004 diagnostic criteria (fever, splenomegaly, cytopenias, hyperferritinemia, hemophagocytosis), treatment (etoposide, dexamethasone, cyclosporine, emapalumab), hematopoietic stem cell transplant.

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📋 30 Clinical Scenarios — Hemophagocytic Lymphohistiocytosis (Nelson 556.2)

📇 High‑Yield Review Cards (Hemophagocytic Lymphohistiocytosis)

🩺 Symptom‑Based Approach: Recognizing HLH

Click any presentation for diagnostic reasoning based on Nelson Ch 556.2.

📋 Stepwise Management of Hemophagocytic Lymphohistiocytosis

    ⚡ Reflex Prompts — HLH Diagnosis & Treatment

    📖 Summary: Hemophagocytic Lymphohistiocytosis — Nelson 22e (556.2)