🍄 Chapter 762 · Nonbacterial Food Poisoning

Nelson Textbook of Pediatrics 22nd Edition | Mushroom poisoning: amatoxin (delayed → liver failure, silibinin+NAC), gyromitrin (seizures → pyridoxine), muscarine (cholinergic → atropine), psilocybin (hallucinations). Other toxins: solanine (green potatoes), ciguatera (mannitol), scombroid (antihistamines), tetrodotoxin (pufferfish, respiratory support), melamine (renal calculi).

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📋 30 Clinical Scenarios — Nonbacterial Food Poisoning

📇 High‑Yield Review Cards

🩺 Clinical Recognition: Food Poisoning Syndromes

Select a food poisoning presentation to review etiology, incubation, and management (Nelson Ch 762).

📋 Stepwise Management of Nonbacterial Food Poisoning

🔑 Key Principles — Chapter 762
• Latency is key: <6h → preformed toxin (scombroid, muscarine, ibotenic acid). >6h → amatoxin, gyromitrin, orellanine.
• Amatoxin (Amanita): Delayed GI (6-24h) → latent period → hepatic failure (day 2-3). Treatment: activated charcoal (repeated), silibinin IV, N-acetylcysteine.
• Gyromitrin: Seizures → pyridoxine 25 mg/kg IV.
• Muscarine: Cholinergic syndrome → atropine 0.01-0.02 mg/kg IV.
• Ciguatera: IV mannitol 0.5-1 g/kg.
• Scombroid: Antihistamines (diphenhydramine).
• Tetrodotoxin: Respiratory support, no antidote.

    ⚡ Reflex Prompts — Food Poisoning Emergencies

    📖 Summary: Nonbacterial Food Poisoning (Nelson 762)