Nelson Textbook of Pediatrics 22nd Edition | HIV infection in children presents with a broad spectrum of clinical manifestations. Infants may have rapid progression (PJP, encephalopathy, failure to thrive). Older children often have recurrent bacterial infections, lymphocytic interstitial pneumonitis (LIP), parotitis, and opportunistic infections (PJP, MAC, CMV, toxoplasmosis). CNS involvement is common. Early diagnosis and cART have dramatically reduced morbidity and mortality.
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