Nelson Textbook of Pediatrics 22nd Edition | Central line-associated bloodstream infection (CLABSI), catheter-associated UTI (CAUTI), ventilator-associated pneumonia (VAP), CSF shunt infections, peritoneal dialysis catheter infections, orthopedic hardware, biofilm, prevention bundles.
🌐 paeds.online — Pakistan's Pediatric Platform| Device | Most Common Pathogens | Key Management |
|---|---|---|
| Central line (CLABSI) | CoNS, S. aureus, Candida, gram-negative bacilli | Vancomycin + antipseudomonal β-lactam; remove line if S. aureus/Candida/persistent |
| CSF shunt | CoNS, S. aureus, gram-negative | Remove shunt, external drain, IV antibiotics (vancomycin + ceftazidime/meropenem) |
| Peritoneal dialysis catheter | CoNS, S. aureus, Pseudomonas, Candida | Intraperitoneal antibiotics; remove catheter if fungal or refractory |
| Urinary catheter (CAUTI) | E. coli, Klebsiella, Enterococcus, Candida | Remove catheter; antibiotics based on culture; avoid treatment for asymptomatic bacteriuria |
| Ventilator (VAP) | Pseudomonas, S. aureus, Enterobacteriaceae | HOB elevation, sedation vacation, oral care; antibiotics based on cultures |
| Orthopedic hardware | CoNS, S. aureus, gram-negative | Debridement, hardware retention vs removal, long-term antibiotics |