🐑 Chapter 278 · Q Fever (Coxiella burnetii)

Nelson Textbook of Pediatrics 22nd Edition | Zoonosis from livestock (sheep, goats, cattle). Transmission: inhalation of contaminated aerosols (placenta, birth fluids). Acute Q fever: fever, headache, atypical pneumonia, hepatitis (granulomas), flu-like illness. Chronic Q fever: culture-negative endocarditis, osteomyelitis (especially in children), vascular infection. Diagnosis: serology (phase II antibodies in acute, phase I antibodies ≥1:800 in chronic). Treatment: doxycycline (acute), doxycycline + hydroxychloroquine (chronic, ≥18 months).

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📋 30 Clinical Scenarios — Q Fever (Chapter 278)

📇 High‑Yield Review Cards (Q Fever)

🩺 Recognizing Q Fever (Acute vs Chronic)

Select a presentation for diagnosis and management.

📋 Step‑by‑Step Management of Q Fever

    📊 Acute vs Chronic Q Fever

    FeatureAcute Q FeverChronic Q Fever

    ⚡ Clinical Reflex Prompts — Q Fever

    📖 Summary: Q Fever (Coxiella burnetii)