Nelson Textbook of Pediatrics 22nd Edition | RSV is the leading cause of bronchiolitis and viral pneumonia in infants <1 year. Epidemiology: winter epidemics, nearly universal infection by age 2. Clinical: rhinorrhea, cough, wheezing, hypoxemia. Complications: apnea in young infants, otitis media, recurrent wheezing. Prevention: palivizumab (high-risk infants), nirsevimab (universal infant prophylaxis), maternal RSVpreF vaccine. Supportive care is mainstay of treatment.
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