Nelson Textbook of Pediatrics 22nd Edition | Polysaccharide encapsulated diplococcus, >90 serotypes, PCV7/13/15/20, invasive disease (meningitis, bacteremia, pneumonia, otitis media), antibiotic resistance (penicillin, cephalosporins), treatment, prevention, high-risk groups.
🌐 paeds.online — Pakistan's Pediatric Platform| Vaccine | Serotypes | Indications |
|---|---|---|
| PCV15 (Prevnar 15) | 15 serotypes (including 19A, 22F, 33F) | Routine infant series (2,4,6,12-15 mo), catch-up |
| PCV20 (Prevnar 20) | 20 serotypes (additional 5) | Routine infant series, high-risk children |
| PPSV23 (Pneumovax 23) | 23 serotypes (plain polysaccharide) | ≥2 years with high-risk conditions (asplenia, CKD, immunocompromised) |