🧬 Chapter 59 · Fragile X Syndromes

Nelson Textbook of Pediatrics 22nd Edition | FMR1 gene CGG repeat expansion: full mutation (>200) causes fragile X syndrome (FXS) — intellectual disability, autism, ADHD, anxiety, macroorchidism, long face, large ears. Premutation (55-200): FXTAS, FXPOI.

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📋 30 Clinical Scenarios — Fragile X Syndromes (Nelson Ch 59)

📇 High‑Yield Review Cards — FXS, FMR1, Full Mutation vs Premutation

🩺 Fragile X Clinical Explorer: phenotype, premutation disorders, management

Click any topic to explore key information from Nelson Ch 59.

🔄 Stepwise Approach: Diagnosis, Management, and Family Counseling for FXS

    ⚡ Reflex Prompts — Clinical decisions in Fragile X syndromes

    📖 Summary: Fragile X Syndromes — Nelson 22nd Ed (Ch 59)