Nelson Textbook of Pediatrics 22nd Edition | Myoclonus: sudden, brief, shock-like involuntary jerks. Classification: physiologic (sleep starts, hiccups), essential (myoclonus-dystonia, DYT11), epileptic (progressive myoclonic epilepsy, JME), symptomatic (opsoclonus-myoclonus, post-hypoxic, metabolic, neurodegenerative). Opsoclonus-myoclonus is a medical emergency (neuroblastoma). Treatment: clonazepam, levetiracetam, valproate, zonisamide.
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