โšช Vitiligo โ€” Chapter 694: Hypopigmented Lesions

Nelson Textbook of Pediatrics 22nd Edition | Vitiligo: acquired autoimmune depigmentation. Generalized (nonsegmental) vs segmental subtypes. Associated with Hashimoto thyroiditis, type 1 diabetes, pernicious anemia, alopecia areata. Treatment: topical corticosteroids, topical calcineurin inhibitors, narrow-band UVB phototherapy, JAK inhibitors (ruxolitinib).

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๐Ÿ“‹ 30 MCQs โ€” Vitiligo (Epidemiology, Subtypes, Associations, Treatment)

๐Ÿ“‡ Highโ€‘Yield Review Cards | Vitiligo

๐Ÿฉบ Vitiligo Presentation โ†’ Subtype & Treatment

Select a vitiligo presentation to learn subtype, associated conditions, and treatment approach.

๐Ÿ“‹ Stepwise Management of Pediatric Vitiligo

๐Ÿ”‘ Key Principles โ€” Nelson 694 (Vitiligo)
โ€ข Generalized vitiligo: Symmetric acrofacial, periorificial. Autoimmune associations (thyroid, T1DM). First-line: topical corticosteroids (mid-high potency) or calcineurin inhibitors (face/intertriginous).
โ€ข Segmental vitiligo: Dermatomal, rapid onset then stabilizes within 1 year. Less autoimmune association. Often resistant to medical therapy; may require surgical grafting.
โ€ข Narrow-band UVB (NB-UVB): First-line for widespread vitiligo (>20% BSA). 2-3 times/week. Repigmentation often begins at 3-6 months.
โ€ข JAK inhibitors: Ruxolitinib cream (1.5%) FDA-approved for non-segmental vitiligo in patients โ‰ฅ12 years.
โ€ข Sun protection: Broad-spectrum SPF 50+ to prevent sunburn and tanning of normal skin (increases contrast).

    โšก Reflex Prompts โ€” Vitiligo Management

    ๐Ÿ“– Summary: Vitiligo (Nelson 694)