🩻 TOACS FCPS Station · Chest X‑ray: Transient Tachypnea of Newborn (TTN)

Nelson · 22nd Ed · “Perihilar streaking, fluid in fissures, term C‑section”
⏱️ 7 minutes · Examiner-led · Observed station
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📷 Chest X‑ray (AP view)

Chest X-ray showing perihilar streaking and fluid in fissures in TTN
Figure 1 · AP chest radiograph · Transient Tachypnea of Newborn (TTN)

🔍 Key radiographic features:

  • Prominent perihilar vascular markings (pulmonary plethora)
  • Fluid in interlobar fissures – especially right horizontal fissure
  • Mild cardiomegaly (enlarged cardiac silhouette)
  • Small pleural effusions (bilateral, small)
  • Clear lung fields – no ground-glass opacities (differentiates from RDS)

📋 Clinical scenario (examiner prompt)

A 39‑week term infant is born by elective Caesarean section without labor. Within 2 hours of birth, the infant develops tachypnoea (respiratory rate 80 breaths/min), mild subcostal retractions, and mild expiratory grunting. The infant is pink in room air with SpO2 92%. On auscultation, breath sounds are clear with no crackles. The chest X‑ray (AP view) is shown.

Elective C‑section Perihilar streaking Fluid in fissures Term infant

🧑‍⚕️ Examiner tasks · TOACS

1. Identify the diagnosis from the X‑ray and clinical context.

2. Describe the X‑ray findings (perihilar streaking, fluid in fissures).

3. Explain the pathophysiology (delayed fetal lung fluid clearance).

4. Discuss management and differential diagnosis (supportive care, exclude sepsis/RDS).

⚠️ Key concept: Transient tachypnea of the newborn (TTN) is the most common cause of tachypnea in term infants. It results from delayed clearance of fetal lung fluid, especially after elective C‑section without labor. The condition is self‑limited (resolves in 24‑72 hours) and requires supportive care.

🎯 Expected answers (for examiners)

  • Diagnosis: Transient tachypnea of the newborn (TTN)
  • X‑ray findings: Prominent perihilar markings, fluid in interlobar fissures (right horizontal), mild cardiomegaly, small pleural effusions
  • Pathophysiology: Lack of labor → absent thoracic squeeze and catecholamine surge → delayed ENaC-mediated lung fluid clearance
  • Management: Supportive care (oxygen if needed, CPAP for moderate distress), NPO with IV fluids if tachypnoeic, exclude sepsis

⚡ Quick FCPS‑style MCQ

The characteristic chest X‑ray finding in TTN is:

A. Ground‑glass opacities with air bronchograms B. Perihilar streaking and fluid in interlobar fissures C. Hyperinflation with flat diaphragms D. Patchy infiltrates with pleural effusion

📌 Topic summary ·

Definition
Delayed fetal lung fluid clearance
Risk factors
Elective C‑section, late preterm, maternal diabetes
X‑ray findings
Perihilar streaking, fluid in fissures
Duration
24‑72 hours (self‑limited)
Treatment
Supportive care, O₂, CPAP if needed
Differential
RDS, sepsis, MAS, PPHN
FeatureTTNRDS
Gestational ageTerm / late pretermPreterm
Risk factorElective C‑sectionSurfactant deficiency
CXRPerihilar streaking, fluid in fissuresGround‑glass, air bronchograms
OnsetFirst 2‑4 hoursImmediately or first hours
Duration24‑72 hoursDays to weeks